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Understanding Side Effects

ZYKADIA® (ceritinib)

Treatment for anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer (NSCLC) means staying on therapy as long as it continues to work or until you develop side effects that do not allow you to continue. When taking ZYKADIA® (ceritinib), there is the potential for side effects to occur. That's why it's important to understand how best to manage them. Some side effects would require ZYKADIA to be discontinued.

Talk to your health care provider about your side effects

Be sure to tell your heath care provider how you are feeling or if you have any concerns about your treatment, especially if you think you are experiencing any treatment side effects.

The most common side effects of ZYKADIA include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach-area pain
  • Tiredness (fatigue)
  • Decreased appetite
  • Weight loss

A few tips for managing some of the gastrointestinal (GI) side effects

You can try taking something to help these types of side effects, such as:

  • Medications to help with nausea or vomiting
  • Medications to help with diarrhea
  • Fluid replacement

Consult your health care provider to create an appropriate side effects management plan. Your health care provider may temporarily interrupt, reduce, or discontinue your dose of ZYKADIA.

Tell your health care provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of ZYKADIA. For more information, ask your health care provider or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.